Inhibition of a multiproduct terpene synthase from Medicago truncatula by 3-bromoprenyl diphosphates
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چکیده
منابع مشابه
Inhibition of a multiproduct terpene synthase from Medicago truncatula by 3-bromoprenyl diphosphates.
The multiproduct sesquiterpene synthase MtTPS5 from Medicago truncatula catalyzes the conversion of farnesyl diphosphate (FDP) into a complex mixture of 27 terpenoids. 3-Bromo substrate analogues of geranyl diphosphate (3-BrGDP) and farnesyl diphosphate (3-BrFDP) were evaluated as substrates of MTPS5 enzyme. Kinetic studies demonstrated that these compounds were highly potent competitive inhibi...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2015
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c5ob00506j